block pain but without the euphoria that leads to addiction
I'm a crystallographer, which indicates I concentrate on taking atomic solution pictures of healthy proteins. I came to be curious about addressing the construct of KOR - when the healthy protein resides in its own energetic condition tied towards a medicine. Construct is actually taken into consideration the gold criterion for finding out exactly just how a medicine interacts along with a receptor and also generates a sign. Towards address the KOR construct, I 1st made the KOR healthy protein making KOR crystals, which contains thousands of numerous KOR particles piled likewise, similar to sodium particles in a sodium crystal. At that point I blasted the crystals along with X-rays towards create an photo of the receptor at atomic amount. The crucial towards these images was actually that I "froze" the KOR healthy proteins in their energetic condition towards recognize exactly just how these receptors engage along with a medicine. A treatment to make cocaine less addict...